MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202641044096 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on April 7, for 'early biofilm detection strip.'
Inventor(s) include Najinaseef Pathoor; Pitchaipillai Sankar Panesh; and Dr. Deepak Nallaswamy Veeraiyan.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses an early biofilm detection strip for rapid and instrument-free identification of biofilm-forming microorganisms. The strip is designed to detect biofilm initiation by selectively capturing early biofilm-associated components and converting these interactions into a visible colorimetric signal. The detection strip comprises a solid support layered with a biofilm-binding layer, a QS indicator layer, and a signal amplification layer. The biofilm-binding layer contains immobilized cationic polymers capable of selectively interacting with extracellular polymeric substances (EPS), including extracellular DNA (eDNA) and acidic polysaccharides, produced during early stages ofbiofilm formation. The QS indicator layer responds to signaling molecules released during biofilm initiation, producing a visible colour change. The signal amplification layer enhances the colorimetric response, enablingrapid naked-eye detection within a short incubation period. The intensity of the developed colour correlates with the biofilm-forming potential of the microorganism, allowing qualitative differentiation between non-biofilm-forming, weak biofilm-forming, and strong biofilm-forming strains. The invention provides a simple, rapid, cost-effective, and portable platform suitable for use in clinical, research, and industrial microbiology settings, and enables timely intervention through early biofilm detection."
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