MUMBAI, India, April 17 -- Intellectual Property India has published a patent application (202631042701 A) filed by Jis University, Kolkata, West Bengal, on April 2, for 'dual channel fluorescent marker for er polarity and viscosity.'

Inventor(s) include Sankar Prasad Bhuniya; and Athul K K.

The application for the patent was published on April 17, under issue no. 16/2026.

According to the abstract released by the Intellectual Property India: "The present disclosure provides an ER-targeted, dual-color fluorescent probe (ER-PV) for the simultaneous monitoring of polarity and micro viscosity within the endoplasmic reticulum of living cells. The probe utilizes a single excitation wavelength to generate two spectrally distinct emission signals, enabling the real-time mapping of the ER microenvironment. The invention allows for the differentiation of normal and cancerous cells based on unique physicochemical signatures and provides a specific diagnostic interface for identifying ferroptosis through simultaneous increases in ER polarity and viscosity. This versatile platform is applicable in high-resolution imaging, drug screening, and the evaluation of ER stress-related pathologies."

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