MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541123883 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 9, 2025, for 'diabetic wound healing activity of panax ginseng root assisted selenium-polycaprolactone nanocomposi.'
Inventor(s) include Azharuddin. R; S. Rajesh Kumar; and Deepak Nallaswamy Veeraiyan.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "Diabetic foot ulcers remain a serious complication of diabetes, associated with delayed healing, recurrent infection, and high amputation risk. To address these challenges, a multifunctional nanocomposite hydrogel was developed by incorporating Panax ginseng-assisted selenium nanoparticles (SeNPs) into a poly caprolactone (PCL)-based thermo sensitive matrix. SeNPs were synthesized via green reduction using ginseng extract, providing intrinsic antioxidant and bioactive properties, and characterized by UV-Vis, DLS, TEM, FTLR, and XRD analyses. The nanocomposite hydro gel exhibited favorable gelation at physiological temperature and sustained nano particle release. In vitro, SeNP@PCL hydrogel demonstrated cytocompatibility, promoted fibroblast migration and angiogenesis, and showed strong antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. In vivo studies using a diabetic mouse excisional wound model revealed significantly enhanced wound closure, collagen deposition, and neovascularization (CD31, VEGF) in treated groups compared to controls. These findings suggest that SeNP-loaded PCL hydrogel offers a novel and effective therapeutic platform by integrating antioxidant, antimicrobial, and regenerative functions, making it highly relevant for clinical translation in diabetic wound management."
Disclaimer: Curated by HT Syndication.
