MUMBAI, India, Aug. 29 -- Intellectual Property India has published a patent application (202421013210 A) filed by Micro Crispr Pvt. Ltd., Vapi, Gujarat, on Feb. 23, 2024, for 'delivery sytem for crispr cas components.'
Inventor(s) include Thakkar, Dr. Parth; Patel, Shivangini; Tiwari, Kajul; Vyas, Dr. Jitendra; and Bilakhia, Aaman.
The application for the patent was published on Aug. 29, under issue no. 35/2025.
According to the abstract released by the Intellectual Property India: "The present disclosure discloses particle (100) including at least one bi-layer outer membrane (110), a plurality of vacuoles (130) and at least one payload (150). The bi-layer outer membrane (110) defining a lumen (110a) including an outer layer (111) and an inner layer (113). The outer layer (111) including at least a plurality of cationic lipids (101), a plurality of neutral lipids (103), a plurality of helper lipid (105), and a plurality of polyethers (107). The vacuoles (130) are disposed within the lumen (110a) defined by the bi-layer outer membrane (110). Each of the vacuole (130) includes a membrane layer (131) defining a lumen (130a) encapsulating the payload (150). Each of the membrane layer (131) and the inner layer (113) including at least the plurality of cationic lipids (101), the plurality of neutral lipids (103), and the plurality of helper lipids (105). The payload (150) includes at least one mRNA and at least one gRNA in a ratio by weight of 1:1, 1:3, 1:7, 1:10, 3:1, 7:1, or 10:1."
Disclaimer: Curated by HT Syndication.
