MUMBAI, India, Feb. 6 -- Intellectual Property India has published a patent application (202641007296 A) filed by Adichunchanagiri Institute Of Medical Sciences, Mandya, Karnataka, on Jan. 24, for 'decision-support system for breast cancer prognosis using wpoi and histopathological markers.'
Inventor(s) include Dr. Amita K; Dr. Rakshitha HB; and Dr. Sanjay M.
The application for the patent was published on Feb. 6, under issue no. 06/2026.
According to the abstract released by the Intellectual Property India: "The present invention proposes a prognostic decision-support system for breast carcinoma that objectively stratifies patients based on recurrence risk. The system automatically extracts histopathological data from surgically excised tumour specimens, including worst pattern of invasion (WPOI), lymphovascular invasion, tumour budding, tumour-infiltrating lymphocytes, lymph node stage, and tumour size. A scoring engine assigns predefined numerical weights to these parameters, generating a composite prognostic score, which is further classified into low, intermediate, or high recurrence risk categories. Results are displayed through a color-coded interface, along with clinical recommendations. It enables prediction of recurrence risk directly from histopathological data without manual score entry. Evaluation of 56 invasive ductal carcinoma cases demonstrated significant associations between higher WPOI grades and aggressive tumour features such as lymphovascular invasion, high tumour budding, larger size, advanced stage, and lower immune response. The system provides an objective, reproducible tool for risk assessment, aiding personalized treatment planning and improving prognostic accuracy in breast carcinoma."
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