MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541122279 A) filed by Malla Reddy (MR) Deemed to be University; Malla Reddy Engineering College For Women; Malla Reddy College Of Engineering And Technology; Malla Reddy Vishwavidyapeeth; and Malla Reddy University, Malkajgiri, Telangana, on Dec. 5, 2025, for 'crispr guided screening system for plant disease resistance genes.'
Inventor(s) include Dr. Katam Naga Lakshman; Ms. Repalle Durga Bhavani; Dr K Srikanth; Mrs. Sheetal Kulkarni; and Dr. K. Asish Vardhan.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "A very effective screening technique is done in response to CRISPR to determine and verify plant items with high level of accuracy and speed. The technology apply a framework editing program with extensive throughout detection to determine genetic loci that can determine resistance of bacterial, fungi, and viruses. This system leverages candidate genomic pathways, which are interconnected with an immune response and uses single-guide RNA, for example the sgRNA libraries are programmed to target certain pathways. The mutagenesis has also been made possible by CRISPR-Cas which can be used to induce mutations into the plant and the phenotypic changes assessed through molecular remarks and digital imaging devices after infection with the pathogens under controlled environments. The received data is filtered through an algorithmic process in comparison with mutation patterns and outcome of resistance, which facilitates a fast gift of gene action. The combined system will have limited editing of the off target, greater reproducibility, and saved time in screening that would otherwise be covered within the traditional mutagenic or hybridization systems. The evaluation could be created to accommodate diverse plant species to enable individual genes to be selectively extracted to meet a specificity towards the resistant crop breeding schemes or period of genetic engineering. The system enables high-fidelity in genome editing with automated analysis of phenotypic analysis of disease resistant gene networks that are essential in ensuring the scale production of agriculture and environmental sustainability when coupled with the high-throughput phenotyping system."
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