MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541122343 A) filed by Aditya Degree & Pg College, Kakinada, Andhra Pradesh, on Dec. 5, 2025, for 'crispr-based gene editing system for targeted treatment of genetic disorders.'
Inventor(s) include Dr. K. Narasimha Murty.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses a CRISPR-based gene editing system (100) designed for precise and targeted correction of genetic mutations associated with hereditary disorders. The system (100) comprises a guide RNA design module (102), a Cas protein complex (104), a vector-based delivery unit (106), a cellular targeting and uptake module (108), and a precision control interface (110). The invention provides an enhanced framework to accurately identify, bind, and repair defective genomic sequences using adaptive AI algorithms that optimize guide RNA specificity and minimize off-target effects. By integrating nanocarrier-based delivery mechanisms and controlled activation of CRISPR components, the invention enables efficient in vivo and in vitro correction of disease-causing alleles. The system is applicable across a broad range of genetic conditions including monogenic disorders, hemoglobinopathies, and metabolic deficiencies, ensuring high therapeutic precision and reduced cytotoxicity during gene therapy interventions."
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