MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202517091628 A) filed by Terremoto Biosciences, Inc., San Francisco, on Sept. 24, for 'covalent modifiers of akt1 and uses thereof.'

Inventor(s) include Chu, Hang; Reisberg, Solomon H.; Zajdlik, Adam; Yang, Kin S.; Carelli, Jordan D.; and Thompson, Peter A.

The application for the patent was published on Oct. 10, under issue no. 41/2025.

According to the abstract released by the Intellectual Property India: "Provided herein are covalent modifiers of AKT1 of Formula (A), (A-1), (I), (I-A), (II), (II-A), (II-B), (III), (III-A), (III-B), (IV), (IV-A), (IV-B), (V), (V-A), (V-B), (VI), (VI-A), (VI-B), (VII), (VII-A), (VII-B), (VIII), (VIII-A), (VIII-B), (IX), (IX-A), (IX-B), (X), (X-A), (X-B), (XI), (XI-A), or (XI-B), and pharmaceutical compositions thereof. In some embodiments, the present disclosure provides methods of modulating AKT1 using a compound or salt of Formula (A), (A-1), (I), (I-A), (II), (II-A), (II-B), (III), (III-A), (III-B), (IV), (IV-A), (IV-B), (V), (V-A), (V-B), (VI), (VI-A), (VI-B), (VII), (VII-A), (VII-B), (VIII), (VIII-A), (VIII-B), (IX), (IX-A), (IX-B), (X), (X-A), (X-B), (XI), (XI-A), or (XI-B), and pharmaceutical compositions thereof."

The patent application was internationally filed on Feb. 23, 2024, under International application No.PCT/US2024/017162.

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