MUMBAI, India, Feb. 27 -- Intellectual Property India has published a patent application (202641018172 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Feb. 18, for 'copper-catalyzed allylic c-h oxidation for synthesis of 2-(tert-butylperoxy)-4-aryl-2h-chromene-3- carbaldehydes.'
Inventor(s) include Grace Victoria Govada; and Dr. Rajasekhara Reddy Sabbasani.
The application for the patent was published on Feb. 27, under issue no. 09/2026.
According to the abstract released by the Intellectual Property India: "A compound having a 2H-chromene core structure (1a, 2a) includes a tert-butylperoxy group attached at the 2-position of the chromene ring through a peroxide linkage, a formyl group at the 3-position of the chromene ring, and a substituent at the 4-position of the chromene ring selected from an aryl group and chloro. A process for synthesizing the compound includes providing a 4-substituted-2H-chromene-3-carbaldehyde substrate (1a), wherein the 4-substituent is selected from an aryl group and chloro, contacting the substrate with a copper catalyst and tert-butyl hydroperoxide as an oxidant in a solvent, heating the reaction mixture to effect allylic C-H oxidation at the 2-position of the chromene ring, and isolating a 2-(tert-butylperoxy)-4-substituted-2H-chromene-3-carbaldehyde product (2a)."
Disclaimer: Curated by HT Syndication.
