MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611024425 A) filed by Institute Of Engineering And Technology; Aryaveer Singh; Dr. Rajiv Kumar Singh; Dr. Ekta Singh; and Prof. Vineet Kansal, Lucknow, Uttar Pradesh, on March 2, for 'computer implemented radiobiological simulation system for cancer treatment planning using universal survival curve model.'
Inventor(s) include Aryaveer Singh; Dr. Rajiv Kumar Singh; Dr. Ekta Singh; and Prof. Vineet Kansal.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "A computer-implemented simulation system for cancer treatment planning based on a Universal Survival Curve radiobiological model is disclosed. The system integrates low-dose linear-quadratic behavior with high-dose multi-target asymptotic response to predict cellular survival over a wide radiation dose range. User-defined biological parameters including radiosensitivity coefficient, characteristic dose, and quasi-threshold dose are processed to generate continuous survival curves applicable to hypofractionated and stereotactic radiotherapy. The simulator computes transition dose and applies model-consistent survival equations to overcome high-dose inaccuracies of conventional linear-quadratic approaches. Statistical regression, sensitivity, elasticity, and heatmap analyses are executed to quantify parameter influence and validate predictive reliability. Experimental verification using non-small cell lung cancer datasets demonstrates close agreement with observed survival trends beyond transition dose. The system is deployable as a standalone application and supports visualization-assisted treatment evaluation, enabling improved dose optimization, biological response assessment, and planning reliability for advanced radiation therapy modalities."
Disclaimer: Curated by HT Syndication.
