MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202611050681 A) filed by Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, on April 21, for 'composition and method for hyperosmolarity-responsive cationic nanoemulsion in dry eye disease.'
Inventor(s) include Dr. Sumita Singh.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a composition and method for an ophthalmic hyperosmolarity-responsive cationic nanoemulsion for the treatment of dry eye disease (DED). The composition comprises cyclosporine A as an immunomodulatory agent and trehalose as an osmoprotective and cytostabilizing agent, formulated within a lipid-based cationic nanoemulsion system. The nanoemulsion includes positively charged droplets having a mean particle size in the range of 70-120 nm and a zeta potential between +20 mV and +40 mV, stabilized using pharmaceutically acceptable lipids, non-ionic surfactants, and a cationic agent. The droplets are surface-modified with a mucoadhesive polymer configured to undergo osmolarity-induced modulation under hyperosmolar tear conditions characteristic of DED, thereby enhancing localized retention and controlled cyclosporine release."
Disclaimer: Curated by HT Syndication.
