MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541123842 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 9, 2025, for 'comparison of peg and pvp coated nanoparticles for mri brain imaging.'

Inventor(s) include Dr Mothish P; Dr. C. R. Vljayalakshml; Dr. Praveen Sharma; and Deepak Nallaswamy Veeraiyan.

The application for the patent was published on Feb. 13, under issue no. 07/2026.

According to the abstract released by the Intellectual Property India: "The present invention discloses graphitic carbon nitride (g-C3N4) modified nanoparticles as a novel, safe, and multifunctional contrast agent for magnetic resonance imaging (MRI) of the brain. The nanoparticles comprise a magnetic core such as iron oxide, copper ferrite, or manganese fenite, coated with a g-C3N4 modification layer. The g-C3N4 enhances biocompatibility, stability, and surface functionality, allowing conjugation with targeting ligands for brain-specific imaging. The invention provides improved MRJ contrast enhancement, lesion detection, and tissue delineation, while reducing cytotoxicity and aggregation compared to unmodified nanoparticles. Additionally, the optical and chemical properties of g-C3N4 enable dual-modality imaging (MRJ + fluorescence/CT). This invention represents a safer, multifunctional nanoplatform for next-generation neuroimaging."

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