MUMBAI, India, Nov. 21 -- Intellectual Property India has published a patent application (202521104723 A) filed by Mr. Sourabh Gajanan Kothiwale; and Dr. Amol Somanath Shete, Karad, Maharashtra, on Oct. 30, for 'chitosan-n-acetyl cysteine lyophilizate for pharmaceutical and agrochemical applications.'

Inventor(s) include Mr. Sourabh Gajanan Kothiwale; and Dr. Amol Somanath Shete.

The application for the patent was published on Nov. 21, under issue no. 47/2025.

According to the abstract released by the Intellectual Property India: "The present invention relates to a chitosan-N-acetyl cysteine (NAC) lyophilizate composition for pharmaceutical and agrochemical applications. The composition is prepared by co-dissolving chitosan and NAC in aqueous medium followed by lyophilization, producing a dry, porous, and amorphous product with enhanced solubility, stability, and bioavailability. The chitosan-NAC complex is formed through ionic and hydrogen bonding without covalent modification, resulting in improved dissolution and rehydration characteristics. The lyophilizate exhibits high water solubility (up to 120 mg/mL), non-hygroscopic behavior, and sustained release of NAC across biological membranes. The formulation demonstrates excellent mucoadhesive and biocompatible properties suitable for ocular, nasal, and wound-healing uses. Additionally, in agrochemical applications, the lyophilizate promotes seed germination, plant growth, and microbial resistance, offering a multifunctional, stable, and bioactive material platform."

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