MUMBAI, India, June 13 -- Intellectual Property India has published a patent application (202517051845 A) filed by Eberhard Karls Universitat Tubingen, Tubingen, Germany, on May 29, for 'chemically modified antisense oligonucleotides (asos) and compositions comprising the same for rna editing.'
Inventor(s) include Stafforst, Thorsten; Pfeiffer, Laura Sophia; and Latifi, Ngadhnjim.
The application for the patent was published on June 13, under issue no. 24/2025.
According to the abstract released by the Intellectual Property India: "The invention relates to chemically modified oligonucleotides comprising a sequence with a length of 23 to 80 nucleotides, capable of binding to a target sequence in a target RNA, comprising a central base triplet (CBT) of 3 nucleotides (I) with the central nucleotide (N0) directly opposite to the target adenosine in the target RNA, wherein the core oligonucleotide comprises the following sequence: (II) comprising different 2' sugar and linkage modifications. The present disclosure also provides oligonucleotides and compositions thereof for use in use in the treatment or prevention of a genetic disorder, condition, or disease. Also provided are methods for editing a target adenosine or deaminating at least one specific adenosine in a target nucleic acid."
The patent application was internationally filed on Nov. 30, 2023, under International application No.PCT/EP2023/083741.
Disclaimer: Curated by HT Syndication.
