MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541123266 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Dec. 6, 2025, for 'carboxymethyl chitosan microscaffolds with zinc and copper ions for bone regeneration.'
Inventor(s) include Dr. Debasish Mishra; Sanjukta Mohan; and Barnika De.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure provides a carboxymethyl chitosan microscaffold composition comprising a carboxymethyl chitosan matrix derived from chitosan through carboxymethylation of amino and hydroxyl groups, zinc ions incorporated into the carboxymethyl chitosan matrix through ionic crosslinking with carboxymethyl groups, copper ions integrated into the carboxymethyl chitosan matrix, and a three-dimensional metal-polymeric lattice structure formed by the zinc ion crosslinking with the carboxymethyl groups. The microscaffold exhibits interconnected pores with diameters ranging from 5 to 15 micrometers, demonstrates antibiofilm activity against Staphylococcus aureus with a biofilm formation index below 1.0, and shows hemolysis percentages below 7% when exposed to human blood. The zinc ions are present at a concentration of 2 M during fabrication and the copper ions are present at a concentration ranging from 0.02 M to 0.1 M during fabrication."
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