MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202531078032 A) filed by Guru Nanak Institute Of Pharmaceutical Science And Technology, Kolkata, West Bengal, on Aug. 17, 2025, for 'carbon quantum dot-based fluorescent sensor for quantitative detection of human chorionic gonadotropin hormone in urine.'
Inventor(s) include Debabrata Ghosh Dastidar; and Arpan Das.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention demonstrates a novel method for quantitative estimation of human chorionic gonadotropin (hCG) hormone in urine utilizing nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs) is disclosed. The invention comprises synthesizing N,S-CQDs through thermal carbonization of citric acid and thiourea (1:500 ratio) at 200 C, yielding quantum dots with 5.04 1 nm average size, 73.43% quantum yield, and -2.88 mV zeta potential. The N,S-CQDs exhibit concentration-dependent fluorescence quenching in the presence of hCG hormone (0-8 IU range), enabling quantitative estimation through Stern-Volmer analysis (quenching constant: 0.4113 in urine). Comprehensive characterization confirms graphene-like structure (0.177 nm lattice spacing), specific elemental composition (C:62.2%, O:34.6%, N:2.8%, S:0.4%), and optimal optical properties (5.1 eV bandgap). The invention provides a simple, sensitive, and cost-effective alternative to conventional pregnancy detection methods, with potential applications in early pregnancy diagnosis and gynecological condition monitoring."
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