Intellectual Property India Publishes Patent Application for 'Capillary Gel Electrophoresis Separation Of Diastereomers Of Phosphorothioated Oligonucleotides' Filed by Synthon B. V.

MUMBAI, India, June 13 -- Intellectual Property India has published a patent application (202517048951 A) filed by Synthon B. V., Nijmegen, Netherlands, on May 21, for 'capillary gel electrophoresis separation of diastereomers of phosphorothioated oligonucleotides.'

Inventor(s) include Durc, Pavol.

The application for the patent was published on June 13, under issue no. 24/2025.

According to the abstract released by the Intellectual Property India: "Method of identification and/or characterization of diastereomers mixtures of phosphorothioate oligonucleotides by capillary gel electrophoresis with a background electrolyte that has a pH 6 to 8, comprising the steps of: a) Preparing a gel matrix by dissolving a water soluble polymer containing a side chain having a functional group that interacts with diastereomers mixture to be analysed in a background electrolyte; b) Introducing the gel matrix in the capillary; c) Introducing the sample of diastereomers mixture of phosphorothioate to capillary; d) Applying an electric field greater than 200 volts/cm of capillary across the gel matrix in the capillary; e) Detecting the individual diastereomers and/or the characteristic groups of partially separated diastereomers of phosphorothioate oligonucleotides."

The patent application was internationally filed on Oct. 23, 2023, under International application No.PCT/EP2023/079519.

Disclaimer: Curated by HT Syndication.