MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202631031260 A) filed by Narula Institute Of Technology, Kolkata, West Bengal, on March 16, for 'cancer treatment modelling framework using allee effects and holling type-iv functional response in discrete time.'
Inventor(s) include Debopriya Dey; Dr. Puja Supakar; and Dr. Shilpi Pal.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "A discrete-time mathematical and computational modeling framework is provided for analyzing tumor growth dynamics and interactions with suppressive agents under physiological and therapeutic constraints. The invention integrates logistic tumor growth with a mate-finding Allee mechanism and a Holling Type-IV functional response to account for reduced proliferation at low densities and immune exhaustion at high tumor loads. Treatment-induced cell removal is modeled as a controlled harvesting mechanism, while suppressive cell populations evolve via a modified Leslie-Gower formulation. The system identifies tumor-free, persistent, and coexistence states through stability analysis, supporting quantitative assessment of extinction thresholds and therapy optimization for personalized medical decision-making."
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