MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541124408 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 10, 2025, for 'bismuth oxide (bi2o3) coated copper ferrite (cufe2o4) nanoparticles for safer and improved magnetic resonance imaging (mri) in brain applications.'
Inventor(s) include Dr. Pujhashrees K; Dr. P Vijayalakshmi; Dr. Yuvaraj M; and Deepak Nallaswamy Veeraiyan.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to the development of Bismuth Oxide (Bi2Ch) coated Copper Ferrite (CuFezCh) nanoparticles as a novel, safer, and multifunctional contrast agent for Magnetic Resonance Imaging (MRI) with particular application in brain imaging. The invention addresses the limitations of conventional gadolinium-based contrast agents by providing, a biocompatible, stable, and non-gadolinium nanomaterial with strong superparamagnetic properties for enhanced T2 contrast. The CuFe2O4 core ensures efficient magnetic responsiveness, while the Bi2C 3 coating enhances biocompatibility, stability, and radiopacity, enabling potential dual-modality imaging (MRI + CT). The nanoparticles demonstrate controlled size distribution, reduced cytotoxicity, and improved dispersion in physiological environments. This invention provides a safer, multifunctional imaging tool for neurological diagnostics, including brain tumors, ischemia, multiple sclerosis, and other cerebrovascular and neurodegenerative conditions."
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