MUMBAI, India, June 27 -- Intellectual Property India has published a patent application (202341088165 A) filed by Natco Pharma Limited, Hyderabad, Telangana, on Dec. 22, 2023, for 'biphenyl pyridine rigid compounds with polycyclic heterocycles useful as dual immune checkpoint inhibitors.'

Inventor(s) include Amala Kompella; Kameswara Rao Vegicherla; Sagar Vijay Kumar Peddakotla; Tirumaleswararao Guntreddi; Lakshmi Prasanna Jasti; Mallika Alvala; Kiran Kumar Babbur; and Venkaiah Chowdary Nannapaneni.

The application for the patent was published on June 27, under issue no. 26/2025.

According to the abstract released by the Intellectual Property India: "This present invention relates to small molecules which are biphenyl pyridine rigid compounds with polycyclic heterocycles therapeutically useful as immune modulators. These compounds disrupt the PD-1/PD-L1 checkpoint pathway, and may also disrupt one or more related checkpoint pathways. These compounds are useful in treating, preventing or ameliorating disorders such as cancer or infections."

Disclaimer: Curated by HT Syndication.