MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541124030 A) filed by Saveetha Institute Of Medical And Technical Sciences, Chennai, Tamil Nadu, on Dec. 9, 2025, for 'biosida-cal: green synthesis of calcium silicate nanoparticle with side cordifolia root extract for enhanced dentin regeneration.'
Inventor(s) include Dr K Ranjima; Dr Aparna Mohan E; and Deepak Nallaswamy Veeraiyan.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "The present invention focuses on the development of BioSida-Cat a novel bioactive nanoparticle-based formulation intended for use in regenerative endodontics. The material is synthesized through a green synthesis approach by integrating calcium silicate nanoparticles (CaSi-NPs) with the ethanolic root extract of Sida cordifolia, a medicinal plant known for its anti-inflammatory, antioxidant, and wound healing properties. Calcium silicate serves as a bioactive scaffold capable of releasing calcium ions that stimulate dentin bridge formation and pulp tissue regeneration, while the phytochemical constituents of Sida cordifolia enhance biocompatibility, angiogenesis, dentinogenesis and antimicrobial activity. The formulation aims to overcome limitations of conventional pulp capping materials by providing a natural, synergistic, and multifunctional approach to promote reparative dentinogenesis and pulp vitality preservation. BioSida-Cal shows promise for application in vital pulp therapy, direct pulp capping, and minimally invasive regenerative dental procedures, offering a sustainable and effective alternative to existing synthetic biomaterials."
Disclaimer: Curated by HT Syndication.
