MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202411104869 A) filed by Indian Institute Of Technology, Rupnagar, Punjab, on Dec. 31, 2024, for 'biomimetic injectable composite for cell delivery in cartilage regeneration and a method thereof.'
Inventor(s) include Anwesha Mukherjee; and Dr. Bodhisatwa Das.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to an injectable photocurable hydrogel composition and a method for preparing the same. The hydrogel composition comprises a methacrylated extracellular matrix analogue comprising gelatin methacryloyl (GelMA), kappa-carrageenan, poly(lactic-co-glycolic acid) (PLGA) nanoparticles encapsulating at least one anti-inflammatory agent, a powdered MEM alpha cell culture medium, a photoinitiator, and potassium chloride as an ionic crosslinker. The composition is reconstitutable with an aqueous medium to form an injectable hydrogel capable of undergoing both photo-crosslinking and ionic crosslinking in situ. The invention further provides a method for preparing the hydrogel by photo-crosslinking the methacrylated component and ionically crosslinking the kappa-carrageenan component. The injectable hydrogel is suitable for localized delivery of anti-inflammatory agents and therapeutic cells, particularly for the treatment of osteoarthritis."
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