MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202641064485 A) filed by Rajagiri College Of Social Sciences, Ernakulam, Kerala, on May 21, for 'biodegradable nanocellulose fibre based bioactive film formulation for treating oral ulcers.'
Inventor(s) include Bindiya. E. S; Jiya Jose; and Aswani. R.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a bioactive nanocellulose-based wound healing formulation for the treatment of oral ulcers, comprising nanocellulose fibers derived from pineapple leaves, sodium alginate, and lactic acid, optionally in combination with quercetin and bromelain. The formulation is processed into a flexible, mucoadhesive film by casting and subsequent ionic crosslinking using calcium chloride. The nanocellulose matrix provides a biocompatible scaffold enabling uniform dispersion and sustained release of the incorporated bioactive agents. Lactic acid imparts significant antibacterial activity against oral pathogens, while quercetin and bromelain contribute anti-inflammatory effects, thereby reducing pain and promoting tissue regeneration. The developed film exhibits desirable physicochemical properties including adequate mechanical strength, swelling capacity, and adhesion to oral mucosa. The synergistic combination of antibacterial and anti-inflammatory components enhances wound healing efficiency and offers a safe and effective alternative to conventional treatments for oral ulcers."
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