MUMBAI, India, Feb. 27 -- Intellectual Property India has published a patent application (202611005506 A) filed by Badal Moreshwarrao Mahakalkar; and Neelam, Mahendragarh, Haryana, on Jan. 20, for 'assessment of anti-bacterial activity of bsa-capped silver nanoparticles synthesized from parthenium hysterophorus- against escherichia coli, staphylococcus aureus, and streptococcus agalactiae.'
Inventor(s) include Neelam; Badal Mahakalkar; Mukesh Meghwal; Daya Patel; Pragati Singh; Pawan Kumar; Sreeja Sudhakaran; and Rupesh Deshmukh.
The application for the patent was published on Feb. 27, under issue no. 09/2026.
According to the abstract released by the Intellectual Property India: "The search for plant-derived antimicrobial agents has gained significant attention in recent years. P. hysterophorus, a medicinal plant traditionally used for treating infectious diseases, remains underexplored for its bioactive properties due to its toxicity and invasiveness. In this study, we investigated the antimicrobial potential of methanolic extracts from P. hysterophorus and silver nanoparticles (AgNPs) synthesized from the extract. While the synthesis of AgNPs from P. hysterophorus helped reduce its inherent toxicity, the reduction was not sufficient for safe therapeutic applications. To further mitigate toxicity and enhance biocompatibility, the synthesized AgNPs were capped with bovine serum albumin (BSA) proteins. Our findings demonstrated significant antimicrobial activity of both the methanolic extract, AgNPs and BSA-Caped AgNPs against Escherichia coli, Staphylococcus aureus, and Streptococcus agalactiae, highlighting their potential as alternative therapeutic agents. The BSA-capped AgNPs exhibited improved stability and reduced toxicity, making them more suitable for biomedical applications."
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