MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202641051711 A) filed by Mohan Babu University, Tirupati, Andhra Pradesh, on April 23, for 'antibacterial and antifungal potential of aqueous methanolic extract of phyllanthus niruri l.'
Inventor(s) include Dr. Janapati Pedda Yanadaiah; and Mr. Kogira Anil.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention pertains to the investigation of antimicrobial properties of an aqueous methanolic extract derived from Phyllanthus niruri L., a herb extensively recognized in traditional Indian medicinal systems. The invention is directed toward addressing the increasing demand for alternative therapeutic agents due to the limitations of conventional antimicrobials, including adverse effects and the rapid emergence of resistant microbial strains. The entire plant material of Phyllanthus niruri was processed through Soxhlet extraction utilizing a methanol and water mixture in the ratio of 70:30. The obtained extract was subjected to systematic evaluation of its inhibitory effects against selected pathogenic microorganisms using established laboratory techniques, including agar diffusion assays and determination of minimum inhibitory concentration (MIC). The test organisms included representative bacterial and fungal strains such as Staphylococcus aureus, Escherichia coli, Candida albicans, and Aspergillus niger. The performance of the extract was benchmarked against recognized antimicrobial agents, namely StreptoPenicillin for bacterial inhibition and Fluconazole for antifungal activity. The results indicated pronounced inhibitory effects, with measurable zones of clearance and effective MIC values, demonstrating comparable performance with the reference standards. The antimicrobial action is attributed to the presence of naturally occurring bioactive constituents, including phenolic compounds, flavonoids, alkaloids, and related secondary metabolites. This invention provides a validated basis for the formulation of plant-derived antimicrobial products using Phyllanthus niruri, with potential applications across pharmaceutical, cosmetic, veterinary, and agricultural domains. The proposed approach offers a safer, sustainable, and biologically effective strategy for the management of microbial infections and supports the advancement of plant-based solutions in addressing antimicrobial resistance."
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