MUMBAI, India, Oct. 31 -- Intellectual Property India has published a patent application (202441032647 A) filed by Cvr Life Sciences Private Limited, Hyderabad, Telangana, on April 24, 2024, for 'an improved process for preparation of tert-butyl ((1r,2s,5s) -2- amino -5- (dimethyl carbamoyl) cyclohexyl) carbamate.'
Inventor(s) include Dr. Anil Kumar Kruthiventi; Dr. Gopikrishna Gaddamanugu; Dr. Sreekanth. Medikonduri; Dr. Hanumaiah Marumamula; Mr. Badike Kuruva Suresh; Mr. Lolam Sandeep; Mr. Kanganti Vishanth; Mr. Sirimalle Saikrishna; Mr. Athkuri Mahipal; and Mr. Nasagoni Ashok.
The application for the patent was published on Oct. 31, under issue no. 44/2025.
According to the abstract released by the Intellectual Property India: "An improved process for the preparation of tert-butyl ((1r,2s,5s)-2-amino-5-(dimethyl carbamoyl) cyclohexyl) carbamate compound of Formula (I) which comprises, brominating the compound of Formula (X) to obtain compound of Formula (IX) hydrolysis of the compound of Formula IX to obtain compound of Formula VIII insitu reacting compound of Formula VIII with ammonium hydroxide to obtain compound of Formula-VII; insitu reacting compound of Formula VII with base to obtain compound of Formula VI; protecting the compound of Formula VI to obtain compound of Formula V; mesylation of the compound of Formula V to obtain compound of Formula IV insitu azidification of the compound of Formula IV to obtain compound of Formula III insitu reduction of the compound of Formula III obtain compound of Formula II; reacting of the compound of Formula II with a base in presence of a solvent to obtain compound of Formula I."
Disclaimer: Curated by HT Syndication.
