MUMBAI, India, Feb. 6 -- Intellectual Property India has published a patent application (202521121098 A) filed by D. Y. Patil Education Society, Kolhapur, Maharashtra, on Dec. 3, 2025, for 'an electrochemical method for early dengue detection in human serum.'
Inventor(s) include Dr. Arpita Pandey-Tiwari; Ms. Susmita Satish Patil; Mr. Sohel Babulal Shaikh; Ms. Vishakha Suryakant Parkhe; and Prof. Dr. Chandrakant Dnyandev Lokhande.
The application for the patent was published on Feb. 6, under issue no. 06/2026.
According to the abstract released by the Intellectual Property India: "The mosquito species Aedes aegypti is the main vector of dengue infection transmission. All over the world dengue burden is increasing constantly. Most of the time, dengue goes undetected and misinterpreted as a normal fever. Dengue in humans can be lethal if not detected timely. Therefore, early and accurate detection of dengue virus is crucial for effective clinical management and reduction of disease burden. In this invention, A highly sensitive electrochemical biosensor for the detection of dengue NS1 protein in human serum using reduced graphene oxide/ gold (rGO/Au)composite thin film as the electrode material is developed. The reduced graphene oxide/ gold (rGO/Au) nanocomposite thin film was synthesized by electrodeposition method, providing excellent conductivity, large surface area, and biocompatibility for biomolecule immobilization. The fabricated thin film electrode was employed for NS 1 detection. Cyclic voltammetry measurements revealed significant changes in charge-transfer resistance upon antigen binding, confirming successful detection. The biosensor exhibited a strong linear correlation between NS1 concentration and electrochemical response with an R2 value of 0.995, demonstrating excellent reproducibility and reliability. The limit of detection (LOD) was determined to be 0.40 g/ml, indicating high sensitivity for early-stage dengue diagnosis. Furthermore, the potential of this platform for rapid, user-friendly, and point-of-care diagnostics. This establishes the reduced graphene oxide/ gold (rGO/Au) thin film-based electrochemical biosensor as a promising candidate for clinical and field applications in dengue detection."
Disclaimer: Curated by HT Syndication.
