MUMBAI, India, Sept. 12 -- Intellectual Property India has published a patent application (202411012562 A) filed by Council Of Scientific And Industrial Research, New Delhi, on Feb. 21, 2024, for 'an autonomous process for selective photo-bromination and nucleophilic substitution of sartan intermediates and their analogues.'
Inventor(s) include Ajay Kumar Singh; Dnyaneshwar Aand; and Abhilash Rana.
The application for the patent was published on Sept. 12, under issue no. 37/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to fabricating a pilot-scale solar tracker continuous flow reactor for the photochemical reaction. The present invention, particularly, relates to a pilot scale process for synthesis of formula 1, which key intermediates of various intermediate of various angiotensin II receptor blockers (ARBs). More particularly, the present invention relates to an integrated continuous flow reactor platform with Bayesian optimization (BO) assisted reaction optimization that can autonomously explore the optimal conditions for photochemical bromination reaction for the synthesis of Formula 1 and Formula 2. Moreover, autonomously explored bromination conditions are seamlessly integrated with continuous flow tools to synthesize, extract, and purify the Angiotensin II receptor blocker intermediate (formula 3)."
Disclaimer: Curated by HT Syndication.
