MUMBAI, India, May 1 -- Intellectual Property India has published a patent application (202611022876 A) filed by Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, on Feb. 26, for 'ai-optimized nasal lipid nanocarrier pharmaceutical composition for targeted nose-to-brain delivery of cns drugs.'
Inventor(s) include Mr. Nishant Gaurav; Dr. Sumita Singh; and Mr. Vishal Kumar Biswkarma.
The application for the patent was published on May 1, under issue no. 18/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a nasal lipid nanocarrier pharmaceutical composition for targeted delivery of central nervous system (CNS) drugs to the brain. The composition comprises at least one CNS-active therapeutic agent encapsulated within lipid nanocarriers formed from one or more solid lipids selected from glyceryl monostearate, stearic acid, and Compritol 888 ATO, optionally in combination with liquid lipids such as oleic acid, Labrafac, or Capryol 90, and stabilized using biocompatible surfactants including Tween 80 or Poloxamer 188. The nanocarriers are engineered to have a particle size in the range of 50-200 nm and are formulated in a nasal-compatible aqueous phase for intranasal administration. Upon administration, the lipid nanocarriers adhere to the nasal mucosa and enable direct nose-to-brain transport of the encapsulated drug via olfactory and trigeminal nerve pathways, thereby bypassing the blood-brain barrier."
Disclaimer: Curated by HT Syndication.
