MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202631059116 A) filed by Polyorbit Private Limited, Bhubaneswar, Orissa, on May 9, for 'a tissue regenerative porous cross-linked polymer scaffold composition and a method of preparing the same.'
Inventor(s) include Dash Mamoni; and Samal Sasmita.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The invention relates to a bioactive scaffold for dental and maxillofacial bone regeneration. The scaffold is formed from a cross linked chitosan-collagen matrix, obtained by methacrylation, crosslinking with PEGDMA and UV induced gelation, and loaded with exosomes derived from human dental pulp stem cells (hDPSCs). The hDPSC exosomes are isolated from conditioned media, characterized by nanoscale size and exosomal markers, and shown to promote proliferation, mineralization and osteogenic gene expression in vitro. The porous scaffold provides mechanical support and controlled release of the exosomes."
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