MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202611052566 A) filed by Chitkara University, Rajpura, Punjab, on April 24, for 'a robust and sensitive hplc analytical method for quantification of chrysin.'
Inventor(s) include Teenu Sharma; Monika; Mansi; Gagandeep Singh; Sushma Devi; Bhupinder Singh; and Thakur Gurjeet Singh.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses an Analytical Quality by Design (AQbD)-enabled High-Performance Liquid Chromatography (HPLC) method for the quantification of Chrysin, developed using a Face-Centred Cubic Design (FCCD) within a Design of Experiments (DoE) framework in compliance with ICH Q14 guidelines. The invention represents the first application of QbD principles to HPLC method development for Chrysin. The organic phase ratio and injection volume were designated as Critical Method Parameters (CMPs), and peak area, tailing factor, and retention time were the Critical Analytical Attributes (CAAs) optimized across 13 experimental runs. The method is rapid, cost-effective, and suited for routine quality control of Chrysin in pharmaceutical and nutraceutical formulations."
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