MUMBAI, India, March 13 -- Intellectual Property India has published a patent application (202641025593 A) filed by Meenakshi Academy Of Higher Education And Research; Meenakshi Ammal Dental College And Hospital, Chennai, Tamil Nadu, on March 4, for 'a process of preparation of oral collagen-nanoparticle bone patch for periodontal and maxillofacial defect regeneration.'
Inventor(s) include Dr. Nikita Ravi; Dr. Aarudra Devi; Dr. Jaideep Mahendra; and Dr. Anitha Logaranjani.
The application for the patent was published on March 13, under issue no. 11/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses a method of preparing a bioactive bone patch for oral and maxillofacial defect regeneration. The method comprises dissolving Type I collagen in acetic acid and neutralizing with sodium hydroxide under sterile conditions to obtain a neutralized collagen slurry. Nano-hydroxyapatite is dispersed into the slurry under continuous stirring to ensure uniform distribution and mechanical reinforcement to form nanoparticle incorporated collagen slurry. Bioactive extracts comprising sterile-filtered black rice extract, walnut extract in phosphate-buffered saline, omega-3 fatty acids emulsified in ethanol, and vitamin D3 solubilized in ethanol are incorporated to form bioactive-loaded collagen matrix with microreservoirs. Glycerin is added as a plasticizer followed by homogenization to form a mixture. The mixture is cast into sterile molds and chemically crosslinked using glutaraldehyde, washed with sterile PBS, to form crosslinked patch and dried to obtain stable bioactive bone patch, which is prehydrated with autologous platelet concentrate prior to clinical application."
Disclaimer: Curated by HT Syndication.
