MUMBAI, India, Jan. 9 -- Intellectual Property India has published a patent application (202541133868 A) filed by Meenakshi Academy Of Higher Education and Research; and Meenakshi Ammal Dental College And Hospital, Chennai, Tamil Nadu, on Dec. 30, 2025, for 'a process of preparation of endodontic irrigant composition for biofilm disruption and product thereof.'
Inventor(s) include Dr. Sooriaprakas Chandrasekaran; Dr. Gopikaraj V; Dr. D. Nalluswamy; and Dr. Arunagirinathan.
The application for the patent was published on Jan. 9, under issue no. 02/2026.
According to the abstract released by the Intellectual Property India: "The present invention discloses a process of preparation of endodontic irrigant composition for biofilm disruption comprises of following steps; a. dispersing Thanga Bhasma in distilled water under continuous magnetic stirring and subjecting to probe sonication followed by cooling to obtain a Thanga Bhasma suspension; b. collecting leaves of Ocimum sanctum and washing with distilled water followed by shade drying and grinding to form a Ocimum sanctum powder followed by dissolving in ethanol and incubating followed by filtering to form a filtrate of ethanolic extract and concentrating to form Ocimum sanctum extract; c. collecting resin from Commiphora myrrha shrub and shade drying followed by grinding to form a Commiphora myrrha powder and dissolving in ethanol followed by incubating and filtering to form a filtrate of ethanolic extract followed by concentrating to form Commiphora myrrha extract; d. mixing the Ocimum sanctum extract, polyethylene glycol (PEG 400), phenoxyethanol and the Commiphora myrrha extract with the Thanga Bhasma suspension under stirring to form a homogeneous mixture followed by adjusting pH using citric acid(acidic) or sodium hydroxide(basic) followed by pre-filtering and filtering using appropriate membrane filter to form an endodontic irrigant followed by filing into a sterile light protective container and storing in appropriate temperature. The present invention also discloses an endodontic irrigant composition for biofilm disruption, prepared by the process as described above."
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