MUMBAI, India, Aug. 1 -- Intellectual Property India has published a patent application (202441005584 A) filed by Apitoria Pharma Private Limited, Hyderabad, Telangana, on Jan. 25, 2024, for 'a process for the preparation of key intermediate of cgrp receptor antagonists.'
Inventor(s) include Gangaram Sathaiah; Rama Krishna Thatavarthy; Guruswamy Batthini; and Praveen Kumar Neela.
The application for the patent was published on Aug. 1, under issue no. 31/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a simple and cost-effective process for the preparation of enantiomerically pure Lactam compound of Formula (II) or pharmaceutically acceptable salt thereof. wherein, X is halogen and n = 0 to 5 The enantiomerically pure Lactam compound of Formula (II) is a key intermediate in the preparation of CGRP (Calcium Gene-related Peptide) receptor antagonists such as Atogepant of Formula (I), Ubrogepant of Formula (I') and likewise."
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