MUMBAI, India, Jan. 9 -- Intellectual Property India has published a patent application (202521129642 A) filed by Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, on Dec. 20, 2025, for 'a pain relieving topical composition, method of preparation and its utility.'

Inventor(s) include Shekhar, Himanshu; Aphale, Parth; and Dokania, Shashank.

The application for the patent was published on Jan. 9, under issue no. 02/2026.

According to the abstract released by the Intellectual Property India: "The present invention discloses a synergistic, pain-relieving topical composition specifically formulated for the management of cyclical and non-cyclical mastalgia, breast tenderness, heaviness, and fibrocystic breast discomfort. The composition comprises Pulsatilla nigricans 3X as the active ingredient, incorporated into a specialized base consisting of wool fat, hard paraffin, white soft paraffin, and cetostearyl alcohol. The method of preparation involves controlled heating, uniform base formation, and a critical mild trituration step to ensure optimal dispersion and skin penetration efficiency. Clinical data demonstrates significant efficacy, achieving an approximate 63% reduction in pain intensity and improved functional outcomes without dependency on hormones. This cost-effective topical solution provides a safe, stable, and reproducible alternative to systemic analgesics."

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