Intellectual Property India Publishes Patent Application for 'A Novel Process For The Preparation Of (6r)-6-(2-(N-(4-(2-(Ethylamino) Ethyl) Benzyl)-N-Ethylamino)-4- Methoxyphenyl)-5,6,7,8-Tetrahydronaphthalen-2-Ol Dihydrochloride And It's Intemediates' Filed by Biophore India Pharmaceuticals Pvt. Ltd.

MUMBAI, India, Oct. 11 -- Intellectual Property India has published a patent application (202441027906 A) filed by Biophore India Pharmaceuticals Pvt. Ltd., Hyderabad, Telangana, on April 4, 2024, for 'a novel process for the preparation of (6r)-6-(2-(n-(4-(2-(ethylamino) ethyl) benzyl)-n-ethylamino)-4- methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride and it's intemediates.'

Inventor(s) include Manik Reddy Pullagurla; Bhaskar Reddy Pitta; and Jagadeesh Babu Rangisetty.

The application for the patent was published on Oct. 10, under issue no. 41/2025.

According to the abstract released by the Intellectual Property India: "The present invention relates to a process for the preparation of (6R)-6-(2-(N-(4-(2-(ethylamino)ethyl)benzyl)-N-ethylamino)-4-methoxyphenyl)-5,6,7,8-tetrahydro nap- hthalen-2-ol dihydrochloride (1) and its novel intermediates thereof. Elacestrant dihydrochloride (1) The present invention further relates to a process for the preparation of intermediates of formula (3), formula (4), formula (4a), formula (5), formula (5a), formula (6), formula (6a), formula (7), formula (7a), formula (9) and formula (10). with enantiomeric excess greater than 50%."

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