MUMBAI, India, July 5 -- Intellectual Property India has published a patent application (202311086104 A) filed by Lovely Professional University, Phagwara, Punjab, on Dec. 17, 2023, for 'a novel process for synthesis of 1h-indole derivatives.'
Inventor(s) include Archana Kumari; Dr. Rajan Kumar; and Dr. Rajesh Kumar Singh.
The application for the patent was published on July 4, under issue no. 27/2025.
According to the abstract released by the Intellectual Property India: "Derivatives of indole have numerous uses in the agrochemical, fragrance, and pharmaceutical industries. They are also utilized as fluorescent labels, polymers, dyes, and colorants. Previous research has identified a number of techniques for synthesizing 3-substituted indole derivatives; however, these techniques have a number of drawbacks, including difficult conditions, lengthy reaction times, the use of dangerous chemicals, and lower yields. In order to overcome the shortcomings of currently available synthetic methods, a practical method for the synthesis of 1H-indole derivatives (104) is required. The current invention relates to the three-component, one-pot synthesis of 1H-indole derivatives (104) using substituted indoles, amines, and a dihalo linker under microwave conditions. The synthesis process is cost effective, used ambient reaction conditions, efficient and less time consuming."
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