MUMBAI, India, Jan. 2 -- Intellectual Property India has published a patent application (202541124015 A) filed by St. Pauls College Of Pharmacy, Hyderabad, Telangana, on Dec. 9, 2025, for 'a method of fabrication of microspheres using semisolid extrusion 3d print technique and ionic gelation.'
Inventor(s) include Dr Kiranmai Mandava; Mrs Bhargavi Nelavetla; Dr Prakash Katakam; and Dr Venkat Ratnam Devadasu.
The application for the patent was published on Jan. 2, under issue no. 01/2026.
According to the abstract released by the Intellectual Property India: "The present invention relates to a method for fabrication of microspheres using a pressure-assisted syringe (PAM) or semisolid extrusion (SSE) 3D printing technique integrated with ionic gelation for drug encapsulation and controlled release applications. The formed microspheres are allowed to gel in the ionic solution for 2 hours, followed by washing and drying (606). Microspheres fabricated by this method (100) exhibit improved sphericity, mechanical stability, and sustained drug release performance (500) compared to conventional syringe extrusion methods. Analytical characterization through SEM (200), FTIR (300), and DSC (400) confirms uniform morphology, absence of chemical interaction, and thermal stability of the components, establishing the technique as a reproducible and scalable approach for pharmaceutical microsphere fabrication."
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