MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202641007478 A) filed by Vellore Institute Of Technology, Vellore, Tamil Nadu, on Jan. 26, for 'a method for preparing dual-drug ethosomal gel formulations.'

Inventor(s) include Dr. Natarajan Chandrasekaran; Dr. George Priya Doss C; Mohanraj Gopikrishnan; and Tanya Diga.

The application for the patent was published on Feb. 13, under issue no. 07/2026.

According to the abstract released by the Intellectual Property India: "The present invention relates to a method for preparing a dual-drug ethosomal gel formulation (100). The method comprises forming an ethanolic lipid phase containing phospholipids, preparing an aqueous phase containing at least two pharmaceutically active agents, and combining the phases under controlled conditions to generate ethanol phospholipid vesicles encapsulating the active agents. The vesicular dispersion is subjected to a size-reduction step to obtain nanoscale ethosomal vesicles with improved uniformity. The stabilized vesicles are subsequently incorporated into a hydrated polymeric gel matrix to obtain a homogeneous ethosomal gel formulation. The method enables controlled vesicle formation, simultaneous encapsulation of multiple active agents, and reproducible integration into a gel system using defined processing parameters. The invention provides a scalable and technically robust preparation method suitable for advanced vesicular gel formulations while maintaining formulation stability and structural integrity."

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