MUMBAI, India, Nov. 21 -- Intellectual Property India has published a patent application (202421038880 A) filed by Amity University Chhattisgarh, Raipur, Chhattisgarh, on May 17, 2024, for 'a method for fabrication of cerium oxide nanoparticle using syzygium cumini seed extract and composition thereof.'
Inventor(s) include Sushant Singh; Bhunesh Sharma; and Sneha Kumari.
The application for the patent was published on Nov. 21, under issue no. 47/2025.
According to the abstract released by the Intellectual Property India: "The present invention describes a green synthesis method for fabricating Cerium Oxide Nanoparticles (CNPs) conjugated with Syzygium cumini seed extract (SC-CNP) and the composition thereof. The method involves Soxhlet extraction of S. cumini seed powder using methanol, followed by the conjugation with Cerium Nitrate Hexahydrate under controlled stirring and thermal conditions. Calcination yields the SC-CNP conjugate, which is characterized via UV-Vis spectroscopy, DLS, and FTIR to confirm successful surface conjugation. Comparative analyses indicate enhanced antioxidant properties of SC-CNP over bare CNPs and crude extract, with superior catalase and superoxide dismutase (SOD) mimetic activities. Additionally, antimicrobial evaluation against E. coli reveals significant inhibition, demonstrating a synergistic effect in SC-CNP. The invention offers a sustainable, plant-based synthesis route with potent antioxidative and antimicrobial capabilities, making it suitable for biomedical and pharmaceutical applications."
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