MUMBAI, India, June 13 -- Intellectual Property India has published a patent application (202517051328 A) filed by Takeda Vaccines, Inc., Cambridge, U.S.A., on May 28, for 'a method for determining the infectivity of a virus.'
Inventor(s) include Livengood, Jill; Gifford, James; Bertolotti-Ciarlet, Andrea; Bustamante-Lopez, Sandra Catalina; Tsuji, Isamu; Watkins, Heather; Dominguez, David; and Norwood, Brooke.
The application for the patent was published on June 13, under issue no. 24/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a method for determining the infectivity of a virus, in particular a flavivirus. Further, a method for determining the titer of a virus-specific antibody in a sample is provided. In addition, the use of the method in the quality control of vaccines and in the diagnosis of an infection are provided as well. The present invention also provides a method for determining the proportion of infectious virus particles in a sample comprising infectious and non-infectious virus particles. The present invention further relates to a maturation assay for determining the average maturation degree. The present invention also relates to novel anti-dengue virus serotype 2 (DENV2) and anti-dengue virus serotype 4 (DENV4) antibodies and antigen binding fragments thereof being useful in the method of the invention. Further, nucleic acids encoding them and host cells comprising them are provided. In addition, the use of the antibodies in the prevention or treatment of dengue disease is provided. Also, diagnostic methods using them and kits comprising them are provided."
The patent application was internationally filed on Nov. 01, 2023, under International application No.PCT/US2023/078311.
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