MUMBAI, India, Jan. 23 -- Intellectual Property India has published a patent application (202511123865 A) filed by Noida Institute Of Engineering & Technology, Greater Noida, Uttar Pradesh, on Dec. 9, 2025, for 'a method for design, synthesis, and evaluation of pyrazoline-piperazine conjugates as anticancer and antibacterial agents.'
Inventor(s) include Mr Himanshu Singh; Dr Avijit Mazumder; and Dr Rajnish Kumar.
The application for the patent was published on Jan. 23, under issue no. 04/2026.
According to the abstract released by the Intellectual Property India: "Disclosed herein is a method for the design, synthesis, and evaluation of pyrazoline-piperazine conjugates as anticancer and antibacterial agents (100) involves designing a series of conjugates (102) by selecting suitable substituted phenyl or heteroaryl groups to enhance biological activity. The designed conjugates are synthesized (104) through a multi-step chemical process that includes formation of the pyrazoline core, functionalization with substituted phenyl groups, and subsequent conjugation with a piperazine moiety. The synthesized conjugates are then purified (106) using appropriate techniques and characterized (108) through spectroscopic, analytical, and elemental analyses to confirm chemical structure and purity. The anticancer activity of these conjugates is evaluated (110) using in vitro cell-based assays on one or more cancer cell lines, while their antibacterial potential is assessed (112) against selected bacterial strains via standard microbiological assays. Finally, structure-activity relationships (SAR) are analyzed (114) to identify conjugates with optimal anticancer and antibacterial efficacy."
Disclaimer: Curated by HT Syndication.
