MUMBAI, India, Jan. 8 -- Intellectual Property India has published a patent application (202511105228 A) filed by Manipal University, Jaipur, Rajasthan, on Oct. 31, 2025, for 'a method and system for predicting organ dysfunction through multi-organ physiologic crosstalk analysis.'
Inventor(s) include Dr. Avichandra Singh Ningthoujam.
The application for the patent was published on Dec. 12, under issue no. 50/2025.
According to the abstract released by the Intellectual Property India: "The present invention relates to a system for the early prediction of organ dysfunction by analyzing the complex crosstalk between multiple physiological systems. The system comprises a dataset that integrate a wide array of data from cardiac, respiratory, renal, neurological, and other systems; an advance machine learning technology trained on extensive datasets from critically ill patients; and a user friendly interface for displaying the prediction result. The core function is to identify subtle, abnormal shifts in the patterns of interaction between organ systems that precede overt clinical symptoms of failure. By recognizing these pre-symptomatic indicators-such as minor, concurrent changes in heart rate variability, urine output, and respiratory rate-the system can forecast the likelihood and timeline of specific organ dysfunctions. This predictive capability allows for earlier, more precise clinical interventions, aiming to improve patient outcomes in critical care settings."
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