MUMBAI, India, Jan. 8 -- Intellectual Property India has published a patent application (202511102918 A) filed by Lovely Professional University, Phagwara, Punjab, on Oct. 25, 2025, for 'a generative artificial intelligence pipeline for discovering antimicrobial peptides.'
Inventor(s) include Dr. Rajeev Sobti; Manish Kumar; Dr. Alok Jain; and Dr. Shailesh Kumar Singh.
The application for the patent was published on Dec. 12, under issue no. 50/2025.
According to the abstract released by the Intellectual Property India: "A generative artificial intelligence pipeline for discovering antimicrobial peptides comprises of a pre-trained protein language model named ProteoGPT 101 that analyzes peptide sequences, multiple specialized sub-models trained through transfer learning to predict antimicrobial activity, filter toxicity, and assess stability, a high- throughput screening 102 component for evaluating hundreds of millions of peptide sequences, a module generating novel AMP candidates with potent antimicrobial effects and low cytotoxicity, and validation 104 modules that confirm antimicrobial efficacy and reduced resistance development against multidrug-resistant bacteria. The pipeline includes mechanisms to evaluate peptide action through cytoplasmic membrane disruption and membrane depolarization, and further in vivo assessment modules enable therapeutic efficacy testing in animal infection models, while ensuring safety by monitoring organ integrity and gut microbiota balance. This system facilitates rapid, efficient discovery of novel AMPs targeting drug-resistant bacterial infections."
Disclaimer: Curated by HT Syndication.