MUMBAI, India, Feb. 13 -- Intellectual Property India has published a patent application (202541006221 A) filed by Neodx Biotech Labs Private Limited, Bangalore, Karnataka, on Jan. 24, 2025, for 'a dihydropyrimidine dehydrogenase mutation real time polymerase chain reaction detection kit and method thereof.'
Inventor(s) include Nalla Reddy Harsha Vardhan; Radhu Kantilal Ladani; and Preetha K.
The application for the patent was published on Feb. 13, under issue no. 07/2026.
According to the abstract released by the Intellectual Property India: "Embodiments of the present disclosure generally relate to a genetic testing technologies used for identifying mutations in genes, and more particularly relate to a dihydropyrimidine dehydrogenase mutation real time polymerase chain reaction detection kit (100) and method thereof. Further, the kit (100) includes three reaction tubes, each provisioned with each primer pair with a Locked Nucleic Acid probe set corresponding to defined subsets of DPYD variants. The kit (100) provides a real time PCR mixture (108) supporting amplification of DPYD target regions, incorporates positive control nucleic acid (110) and internal amplification control DPYD target region (112) for assay verification. Each probe set supports allele-specific fluorescence generation for wild type and mutant alleles during a unified PCR run. Further, the associated method (1200) supports genomic DNA extraction, aliquoting, thermal cycling, fluorescence acquisition, threshold cycle determination, allelic discrimination, and genotype assignment, enabling reliable identification of DPYD variants relevant to pharmacogenomic decision making."
Disclaimer: Curated by HT Syndication.
