MUMBAI, India, Aug. 8 -- Intellectual Property India has published a patent application (202441007308 A) filed by Manipal Academy Of Higher Education, Manipal, Karnataka, on Feb. 2, 2024, for 'a cellular placental membrane for guided tissue and bone regeneration and method of preparation thereof.'

Inventor(s) include Prashanthi S. Madhyastha; Rachel Sarah Vinodhini; Bhisham Narayan Singh; Rajalakshmanan Eswaramoorthy; and Manjunath Pattabhi.

The application for the patent was published on Aug. 8, under issue no. 32/2025.

According to the abstract released by the Intellectual Property India: "The present invention is related to a cellular placental membrane for guided tissue and bone regeneration and method of preparation thereof. Periodontal regeneration techniques like Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR), reconstruct and restore the lost tooth-supporting structures by the use of barrier membrane scaffolds. Placental membranes, which include the amniotic and chorionic membranes, have excellent regenerative properties and are currently used as GTR and GBR membranes. However, the currently available commercial membranes are expensive, non-porous and do not undergo the process of decellularization, which is important to prevent immunogenic reactions in the host although placental membranes have low immunogenic properties. The proposed invention is developed to produce a bioresorbable, acellular, porous, 3-dimensional barrier membrane from the extracellular matrices amnion and chorion of the human placenta that would aid in better cellular attachment, proliferation, and regeneration of tissues for GTR and GBR applications."

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