MUMBAI, India, May 29 -- Intellectual Property India has published a patent application (202641061608 A) filed by Indian Institute Of Technology, Palakkad, Kerala, on May 14, for 'a biocompatible antibacterial nanoparticle composition and method for preparing the same.'
Inventor(s) include Vishnu N. Vijayan; Athira; Jissy Anna George; and Sushabhan Sadhukhan.
The application for the patent was published on May 29, under issue no. 22/2026.
According to the abstract released by the Intellectual Property India: "The present disclosure relates to the field of nanotechnology and antimicrobial materials. The invention provides a biocompatible antibacterial nanoparticle composition comprising gallium ions coordinated with epigallocatechin-3-gallate (EGCG) to form gallium-EGCG nanoparticles, and a method for preparing the same. The nanoparticles exhibit spherical morphology, nanoscale size, and iron-dependent antibacterial activity through disruption of bacterial iron metabolism. The composition combines antibacterial and antioxidant properties within a single nanoscale platform, utilizes iron-mimicking behavior of gallium ions for bacterial uptake, and is effective against Gram-positive and Gram-negative bacteria, including drug-resistant strains. The nanoparticles inhibit bacterial growth and biofilm formation under physiologically relevant conditions while maintaining low cytotoxicity toward mammalian cells. The composition is suitable for incorporation into pharmaceutical formulations, biomedical coatings, wound-healing compositions, or antimicrobial surfaces."
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