MUMBAI, India, July 25 -- Intellectual Property India has published a patent application (202517060668 A) filed by Fudan University; and East China Normal University, Shanghai, on June 25, for '7-azaindole compounds, preparation method therefor, and use thereof.'
Inventor(s) include Dong, Xiaochun; Zhang, Xiongwen; Zhao, Weili; Sun, Weikuan; Ruan, Li; Wang, Xiaoting; Fan, Rong; and Gu, Xiaofan.
The application for the patent was published on July 25, under issue no. 30/2025.
According to the abstract released by the Intellectual Property India: "Disclosed in the present invention are 7-azaindole compounds, a preparation method therefor, and the use thereof, belonging to the field of drug synthesis. The present invention particularly relates to 7-azaindole compounds containing pyrazole or indole substitution represented by general formula (I), a preparation method therefor, and the use thereof in medicine. The compounds of the present invention alleviate cancer cachexia skeletal muscle atrophy by means of inhibiting ActRIIB protein in the MSTN pathway, thereby achieving a remarkable anti-cancer-cachexia effect. Experimental results show that the compounds have good anti-cachexia activity and thus can further be used for preparing novel anti-cachexia drugs."
The patent application was internationally filed on Nov. 29, 2023, under International application No.PCT/CN2023/134906.
Disclaimer: Curated by HT Syndication.
