Intellectual Property India Publishes Patent Application for “a Transition Metal Complex To Form Carbendazim, Mebendazole And Related Bioactive Compounds And Methods Of Preparation Thereof ”

MUMBAI, India, Sept. 7 -- Intellectual Property India has published a patent application (202621088028 A) filed by Indian Institute Of Technology Bombay on July 18, 2026, for “a Transition Metal Complex To Form Carbendazim, Mebendazole And Related Bioactive Compounds And Methods Of Preparation Thereof ”.

Inventors include Rohan Dey; and Prasenjit Ghosh.

The application for the patent was published on September 04, 2026, under issue no. 36/2026.

Abstract: ABSTRACT A TRANSITION METAL COMPLEX TO FORM CARBENDAZIM, MEBENDAZOLE AND RELATED BIOACTIVE COMPOUNDS AND METHODS OF PREPARATION THEREOF The present invention relates to a transition metal complex comprising pyridine-tethered 1, 2-diaminocycloalkane ligand of cobalt and particularly to the compounds of formulation [N1,N1-(CH2Ph)2-N2-(pyridin-2-CH2)-cyclohexane-1,2-diamine]CoX2 [where X = Cl (2), Br (3)] which catalyse the organic reaction, namely, an aerobic oxidative coupling of isonitriles with o-phenylenediamines yielding N-(alkyl)-2-aminobenzimidazole derivatives, which upon dealkylation and followed by an acylation reaction conveniently get converted to a fungicide drug, Carbendazim, an antiparasitic drug, Mebendazole and related bioactive compounds. Figure. 4.

Disclaimer: Curated by HT Syndication.