MUMBAI, India, Sept. 12 -- Intellectual Property India has published a patent application (202547079992 A) filed by Shanghai Research And Develop Center Of Industrial Biotechnology; and Cas Center For Excellence In Molecular Plant Sciences, Chinese Academy Of Sciences, Shanghai, on Aug. 22, for 'method for improving rate of xylose and arabinose utilization in saccharomyces cerevisiae.'
Inventor(s) include Yang, Sheng; Qian, Fenghui; Jiang, Yu; Zhang, Yiwen; and Yang, Junjie.
The application for the patent was published on Sept. 12, under issue no. 37/2025.
According to the abstract released by the Intellectual Property India: "The provided is a method for improving the rate of glucose, xylose and arabinose utilization in Saccharomyces cerevisiae, comprising the following steps: using Saccharomyces cerevisiae with the ability to convert xylose and/or arabinose into ethanol, lactic acid, butanedioic acid, farnesene or isobutanol as a chassis cell to make the following mode of modifications in its genome: A. a mutation in the TRK1 gene for the potassium ion intracellular transporter protein, resulting in an increase in intracellular potassium ion/sodium ion ratio in Saccharomyces cerevisiae, and/or B. a mutation in the PUF2 gene for mRNA-binding protein or PUF2 gene knockout, resulting in PUF2 inactivation, deletion, reduced function, or down-regulated mRNA translation strength. The recombinant Saccharomyces cerevisiae constructed can utilize the cellulase hydrolysate comprising glucose, xylose and/or arabinose to produce ethanol, lactic acid, butanedioic acid, farnesene or isobutanol by fermentation, and has broad application prospects."
The patent application was internationally filed on Feb. 01, 2024, under International application No.PCT/CN2024/075298.
Disclaimer: Curated by HT Syndication.
